Can the PI of a Multidisciplinary project be from any department/unit participating in the project, or must the PI be from a discipline eligible during the funding cycle?

The PI of a Multidisciplinary project may be from any participating department, but the proposal must be rooted in a discipline eligible in the funding cycle and convincingly argue that project benefits will accrue significantly, and not just incidentally or tangentally, to one or more eligible disciplines. External reviewers will assess and make determinations about the degree to which a proposal demonstrates its eligibility per the criteria set forth in the RFP.